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Exploring small differences between animal responses, when there is significant variance in behavioral responses between individuals, often with a limited number of specimens used, requires statistical proof and the use of sufficient numbers of replicates

Toxicol Sci 2004;82:37480 [DOI] [PubMed] [Google Scholar] 83.Wolf KK, Wood SG, Hunt JA, Walton-Strong BW, Yasuda K, Lan L, Duan SX, Hao Q, Wrighton SA, Jeffery EH, Evans RM, Szakacs JG, von Moltke LL, Greenblatt DJ, Court MH, Schuetz EG, Sinclair PR, Sinclair JF

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Encapsulating BBR in liquid crystal nanoparticles (LCNs) of phytotriol showed more robust anti-inflammatory and antioxidant activity in lipopolysaccharide-induced RAW246.7 macrophages in vitro (Alnuqaydan et al., 2022)

Adjust the dosage based on the animal's weight, age, and health condition