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It is important to review the peripheral smear and hemogram along with HPLC before arriving at a conclusion because though HPLC is the gold standard in diagnosing hemoglobinopathies, the morphological changes in RBCs can only be ascertained on PS

They further suggested ApoB may be the main driver of atherosclerosis

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The study also pointed out that only a small portion (less than 3%) of the participants were over age 75, and advised caution in prescribing for these populations

Symptoms such as chest discomfort, shortness of breath, or reduced exercise capacity should be assessed by a doctor rather than self-treated with supplements