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These chronic attributes are generally associated with selective degeneration of dopaminergic neurons, corollary de-pigmentation of substantia nigra pars compacta (SNpc) and concomitant accumulation of -synuclein in insoluble inclusions called Lewy bodies 2,3

However, one shot every two to four weeks is enough

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Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword

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