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A comprehensive metabolic evaluation helps distinguish whether combined therapy addresses a genuine biomarker-driven need or represents empirical experimentation

The mechanisms of how this happens is not fully known yet, says Amit Zachariah, MD, a cardiologist with Duly based in Schaumburg, Illinois

Key secondary endpoints included number of participants achieving 10%, 15%, 20% and 25% weight loss, respectively

doi: 10.1056/NEJMoa1109333 28 ArslanianSAHannonTZeitlerPChaoLCBoucher-BerryCBarrientos-PerezMet al

Data integration helps to inform a more complete picture of public health so that public health professionals can monitor emerging threats to health and safety