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This mechanism is believed to play a key role in the pathogenesis of TED and is the basis for emergent therapeutic alternatives in patients with TED and, maybe, dermopathy

Goblet cells also have a role in the surveillance of harmful stimuli present in the gut lumen through antigen uptake and transport to underlying components of the subepithelial immune system such as dendritic cells (McDole et al

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In March 2025, a major new study was published in the journal Nature Medicine

However, alcohol might also make depression worse in some cases