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The strategy of covalently conjugating metal-based anticancer agents to amphiphilic polymers, that could self-assemble into nanoparticles, could present a method for the tumor-selective anticancer therapy

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If the cause isn't dietary then it is an absorption problem so you need to find another way of replenishing B12 initially

[14] Following World War II, chelation therapy was used to treat workers who had painted United States naval vessels with lead-based paints

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Injections can be weekly while refills are made on follow-ups.