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Diagnosis of vitamin B12 deficiency in patients with myeloproliferative disorders

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The consequences of NNMT overexpression create a metabolic feedback loop that promotes and maintains obesity

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The introduction of the R17 Cagri- E14 Cagri intra-peptide ionic lock energetically favours the formation of a predominant bypass conformation at the CTR, which, together with the P37 substitution and the effects induced by the N-terminal acylation, likely underlies its improved potency over rAmy at this receptor