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Escalate: Increase by 24 mg every 4 weeks as tolerated

The Complete Response Letter did not note any issues with the biosimilars clinical efficacy or safety, trial design, labeling, drug substance manufacturing or device design or manufacturing, Coherus stated in a press release

The team concluded that these results point to an "antimutagenic effect," which they hypothesize could be the source of epitalon's geroprotective abilities

Someone working in a highly regulated safety-sensitive industry has a different testing framework than someone in a standard office environment

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