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6,7,8,9,10 Moreover, through NAMPT activation, SIRT1 is involved in the regulation of several stemness signaling factors, such as the tumor suppressor Hippo pathway, 184 c-Myc-mediated OCT4 interaction, 78,185 NICD from the Notch pathway and Gli1 and Gli2 from the Hedgehog pathway

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Available: [3] P

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However, higher doses increase cost without established evidence of proportionally increased benefit

While large human trials are still pending, Dihexa is already showing promise as part of cognitive optimization and neuroprotective strategies in clinical settings