doi: 10.1016/j.jare.2024.04.012 Summary Keywords osteoarthritis, gut-joint axis, ferroptosis, gut microbiota, therapeutic strategies Citation Wang T, Xu Y, Zha H and Wu L (2025) The gut microbiota-ferroptosis axis: a hypothesis for osteoarthritis pathogenesis and therapeutic implications
Our GLP-1 agonist therapies, Semaglutide and Tirzepatide for weight loss, offer a proven path to lasting weight loss
Background Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
Environmental Science & Technology, 851(2): 158247 Prasedya E, Kurniawan N, Kirana I, Ardiana N, Abidin A, Ilhami B, Jupri A, Widyastuti S, Sunarpi H, Nikmatullah A (2022)
A study from the Dutch EB registry found an overall EB incidence of 41.3 per million live births and 22.4 per million population.[129] Similarly, a German study found an EB incidence of 45.1 per million live births.[130] However, a study from England and Wales found a much higher EB incidence of 67.8 per million population.[131] In the most extreme cases, EB can result in the congenital absence of the skin.[132] Dystrophic EB and junctional EB are associated with an increased risk of skin cancer, particularly SCC.[133] While the type of EB can be difficult to determine clinically, next-generation sequencing can define the EB subtype in up to 90% of cases.[134] Diagnosis of EB may be accomplished by immunofluorescence or electron microscopy.[135] The types of EB, pathogenic variants involved, and phenotypic characteristics are detailed in the following review.[136] For more information, see the EB simplex section
BPC stands for Body Protective Compound, acquiring its name from its potent ability to quickly heal the body
