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It is worth noting that, consistent with experience across the GLP-1/GIP class, weight loss in people with type 2 diabetes may be somewhat smaller in magnitude compared with those with obesity alone

As mentioned earlier, a lack of adenosylcobalamin leads to the accumulation of toxic methylmalonic acid (MMA), which forces the body to build weak, abnormal fatty acids into the nerve sheaths

It should be started at 0.6 mg daily for 1 week

First-trimester exposure and major malformations similarly showed no significant association, a result confirmed in a sensitivity analysis restricted to adjusted estimates

Monitoring may be appropriate in higher-risk individuals