It is a 42-amino acid peptide secreted by the K-cells, present in high density in the duodenum and upper jejunum, following oral ingestion of nutrients such as glucose, amino acids, and long-chain fatty acids (Fig
Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, Castoria G, Migliaccio A
It is also important in maintaining cell membrane stability through its involvement in acetylation of membrane phospholipids and amphiphilic actions [31, 32]
As ALS progresses, over 80% of patients develop difficulty swallowing (dysphagia), and many also experience increased metabolism, which raises their calorie needs by about 1520% more normal (Dupuis and Chio, 2023)
Never discontinue prescribed GLP-1 therapy without medical guidance, as abrupt cessation may affect glycaemic control or weight management goals
While dental implants are a superior alternative, dentures remain a popular and cost-effective choice for many elderly individuals seeking to maintain their quality of life