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Gaddum's Pharmacology

Due to its multiple amide groups and hydroxyl functionality, Dihexa possesses several potential hydrogen bond donors and acceptors

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The class includes several medications: semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and liraglutide (Saxenda)

Understanding this mechanism helps to explain why Retatrutide is so effective and can guide the development of even better medicines in the future