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Although a statistically significant reduction was observed in Sequence 2 (i.e., GSH-C4-first) from baseline to the intermediate timepoint (p = 0.0312), only a modest decrease in the FACES score was noted in Sequence 1 (i.e., HA-first) from the intermediate to the final timepoint (p = 0.0625)

Figure 2 3.3.2 Tumor necrosis factor-alpha The comparison of TNF- against placebo showed a significant reduction ( Figure 3A ) (SMD = -0.61

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Based on the results presented here, we would predict participants with poorer insulin sensitivity would show a corresponding shift in acceptance bias