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The company told Reuters that it stands behind the advertisements because they reflect results from the SURMOUNT-5 trial

Most research to date is in animal models

doi: 10.1039/b908260c

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A clinical trial published in the Journal of Aging Science examining 40 women aged 40-65 demonstrated that topical GHK-Cu applied twice daily for 8 weeks "reduced wrinkle volume by 55.8% and wrinkle depth by 32.8%." The peptide appears to stimulate collagen and elastin production, enhance wound healing, and provide antioxidant effects