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The procedure is carefully controlled for temperature and timing, with incubations typically ranging from 1 to 2 h at room temperature to overnight settings at 4C, depending on the target analyte

doi: 10.1111/j.1600-079X.2005.00276.x 71 ManchesterLCTanDXReiterRJParkWMonisKQiW

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In cases of suspected cobalt hypersensitivity, an intradermal test dose should be administered

When a compound has such a narrow target, the potential for off-target side effects is inherently limited

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