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GLP-1 Drugs Show Promise for Pain Management and Opioid Addiction A new class of diabetes and weight-loss drugs is drawing attention from researchers, and the early data on opioid addiction may be the most compelling signal yet

Elsaid: The ESSENCE trial showed that semaglutide improves liver histology in fibrotic MASH, which is why the FDA approved it for that use

The largest longitudinal study on multi-year supplementation remains limited

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STEP-HFpEF was a randomised, controlled trial designed to find out whether semaglutide for 52 weeks could improve heart failure symptoms and physical function in obese, non-diabetic patients with heart failure with preserved ejection fraction (HFpEF)

This finding suggests that impurities disrupting the tolerogenic epitope could contribute to immunogenicity in clinical use