Anyone participating in a clinical trial who experiences persistent or severe gastrointestinal symptoms, unexplained abdominal pain (which may indicate pancreatitis or gallbladder disease), signs of dehydration, or other concerning symptoms should contact their supervising healthcare team promptly
The tradeoff is more side effects early on, which is why the escalation schedule exists
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In: Taylor JB, Triggle DJBT-CMCII (eds) Elsevier, Oxford, pp 417458 Schorr AB, Ofan R (2012) Simultaneous use of two external subcutaneous pumps delivering insulin and SYMLIN: use of a double-pump system
Semaglutide works by triggering GLP-1 receptors in the brain, which reduces food intake and increases feelings of fullness
Vomiting: Generally less frequent than nausea, usually occurring if a patient overeats