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Kim, a department manager in their 40s at a company, recently bought four new summer shirts after losing 5 kilograms (11 pounds) in three months while taking a prescription weight-loss drug

Bottom line: Calorie restriction (defined as anything less than 1,500 calories per day) or any diet that is considered a low calorie diet will ultimately make your leptin resistance worse over time

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Others may not see a significant change if their nausea has already resolved through adaptation

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