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Moreover, overproduction of ROS has an impact to enhance the cancer cell proliferation, migration, metastasis, invasiveness and poor prognosis through many cellular mechanisms like matrix degradation, cell-cell contact, cell remodelling, as well as regulation of gene expression [54]

In the realm of natural compounds, biochanin A (BCA), extracted from Astragalus, protects against bone loss by inhibiting TfR1 and enhancing FPN, thereby reducing intracellular iron levels

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RCT study of moderate-quality indicated that L-carnitine did not influence albumin, C-reactive protein (CRP), interleukin-6 (IL-6), and quality of life