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Starting Dose 20 units (0.6mg) Form Injectable vial (5mL, 3mg/mL, 15mg total) Dosing Protocol 20 units subcutaneous injection daily, Monday to Friday

Thus, inhibiting xCT by small molecule compounds, such as Erastin, or directly removing cystine from the cell culture medium can induce the occurrence of ferroptosis (Figure 1)

Relatedly, our group demonstrated that the antioxidative and anti-inflammatory properties of l-Carnitine protect RTCs from PFOS-mediated renal injury 2 and fibrosis through a PPAR-dependent mechanism 13

10.1097/01.pgp.0000236951.33914.1b Int

Curr Issues Mol Biol 2022;44:3465-80.ArticlePubMedPMC 41

Zalaudek I, Grinschgl S, Argenziano G, et al