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When these vessels become blocked or damagedwhether due to diabetes, hypertension, or other factorsthe oxygen-starved retinal tissue can deteriorate, leading to irreversible vision impairment

Ideal candidates include adults with obesity-related moderate-to-severe psoriasis who are interested in weight loss or candidates with mild type 2 diabetes on oral agents when the treatment may support dermatologic goals

If symptoms persist, dose adjustments or switching to a different medication may be necessary

Curr Neurol Neurosci Rep (2009) 9(4):30712

Additionally, pretibial myxedema occurs Due to dermal fibroblast stimulation that leads to GAGs deposition in the connective tissue

Walking more, taking stairs, and staying active throughout the day can add several hundred calories of expenditure without formal exercise sessions