The study also revealed a statistically significant drop in IOP after starting GLP-1 receptor agonist treatment, especially in those with a history of glaucoma or pre-existing excessive IOP. The researchers also found that GLP-1 agonist use in the management of type 2 diabetes may have possible cardiovascular advantages
Serious allergic reactions (anaphylaxis or angioedema) are rare but require emergency treatment
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In addition to the effects of SMAD3 antagonism on MMP9, treatment with both TGF 1 and SIS3 was also able to rescue the downregulation of claudin-5 mRNA and protein (Figures 6a and b) compared with TGF 1 treatment alone
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