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Description

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Acknowledgements We would like to acknowledge Dr

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328 In ALS, HSBP8 protects against aggregation of TDP-43 and its cleavage products (TDP-25 and TDP-35) by promoting their removal via autophagy, further illustrating the tight functional coupling between sHSPs and degradative pathways

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By modulating various metabolic pathways, MOTS-c influences processes such as glucose metabolism, insulin sensitivity, and fat oxidation

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