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Glutathione mutants showed also a higher susceptibility to SFN treatment To address the question if the more susceptible phenotype of glutathione mutants towards AITC was unique for this GHP, sulforaphane (SFN), an aliphatic ITC possessing a longer side chain than AITC, was tested

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In the liver, it binds to heavy metals, environmental toxins, and metabolic waste products, making them water-soluble so they can be safely excreted through bile and urine

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Additionally, it is used in the biosynthesis of glutathione [33, 35]

3 Molecular mechanisms of oxidative stress-induced sperm damage Oxidative stress has been extensively recognized as a significant contributor to male infertility, particularly through its damaging effects on spermatozoa