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Their findings revealed that astragaloside IV (AS-IV) increased Sirt1/Nrf2 activity, ultimately resulting in increased GPX4 expression, which decreased retinal lipid peroxidation

Research in aging mouse models shows that MOTS-c administration suppresses SASP markers and reduces the burden of senescent cells in metabolically active tissues [2]

Not suggested

Corticosteroid and NAC nasal douching significantly reduced symptom severity more than two-fold, resolved mucosal edema, and restored mucociliary function in recurrent acute rhinosinusitis patients compared to steroid with ambroxol, leading to better long-term satisfaction (121)

Nothing else added during this phase

Collectively, these data suggested that GPR146 likely regulates PKC signaling pathway through coupling to Gq during adipogenesis