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A systematic review integrating data from 165 studies involving 9,923,461 patients showed that among COVID-19 survivors, the prevalence rates for depression and anxiety were both 23%, and sleep disorders 45% (83) ( Table 1 )

Similarly, measurements of MDA levels, CoQ10 activity, and NAD+/NADH ratios yielded consistent results, demonstrating that PPARa activation enhanced the FSP1-CoQ10-NAD(P)H pathway and thereby reduced lipid peroxidation level (Fig

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