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Its the most common medication that I get asked about, says Dr

FDA-approved for type 2 diabetes and for reducing the risk of major adverse cardiovascular events in certain adults with type 2 diabetes and established cardiovascular disease

PMID 19016852

The question of whether retatrutide causes fatigue comes up frequently

The SmPC notes an interaction with increased thyroxine exposure, so discuss the optimal timing of both medications with your GP, as they may need to be spaced further apart and thyroid function monitoring may be required

However, the weight loss possible with Wegovy will also lead to substantial improvement of overall health and decrease in health risks for most obese people