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Emerging Diversity in Lipid-Protein Interactions

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In a last set of studies we tested whether the circulating d9-carnitine observed (via endogenous pathway) following d9-BB ingestion might reenter the intestinal lumen (via diffusion or entero-hepatic cycling) to ultimately produce d9-TMA and d9-TMAO

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We used CRISPR/Cas9 to generate multiple clonal BT-549 cell lines deficient in ACSL1 (Fig