Review medication, dosing, and handling decisions with a licensed healthcare professional
The PlexusDx Precision Peptide Genetic Test analyzes 14 biological pathways and 49 peptides, including variants in GLP1R, GIPR, and genes affecting dopamine and serotonin regulation
and Neel, B.G
Ask about the specific medication being consideredwhether semaglutide (Wegovy) or tirzepatide (Zepbound), which are FDA-approved for chronic weight managementand how your cholecystectomy history might influence the choice
By modulating the release of dopamine, the medication may make sweet foods feel less rewarding. If the brain no longer receives a massive surge of pleasure from a sugary snack, the motivation to seek out that snack begins to fade
The EMPA-KIDNEY trial enrolled a larger proportion of participants without diabetes mellitus and included individuals with lower mean eGFR (37.3 mL/min/1.73 m) and median UACR (329 mg/g) compared to DAPA-CKD