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Notably, thyroid hormones may facilitate augmented carnitine synthesis in the liver by increasing -butyrobetaine hydroxylase (BBD) activity and gene expression, which may constitute a feedback regulatory loop between thyroid hormones and carnitine [80]

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Collagen is a type of protein naturally found in connective tissues, tendons, blood vessels, and especially the skin

61% of patients have reported being bedbound on their worst days (41) and at least one-quarter of ME/CFS patients have recounted being housebound or bedbound at some point in their lives (42)

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Lomonosova YN, Kalamkarov GR, Bugrova AE, Shevchenko TF, Kartashkina NL, Lysenko EA, Shvets VI, Nemirovskaya TL (2011) Protective effect of L-Arginine administration on proteins of unloaded m