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Neelakantan et al., 2018

In the human studies FDA identified covering rectal, intra-articular, intravesical, and intravenous administration no serious adverse events were reported, and the most common side effects were headache and flatulence at rates comparable to placebo

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In the same study, fer-1 accelerated wound healing in diabetic rats by inhibiting ferroptosis by activating the PI3K/Akt signaling pathway