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[DOI] [PMC free article] [PubMed] [Google Scholar] [14].Shoenfeld Y

The anti-nociceptive effects of NaBPC157 were evaluated in comparison with aspirin and morphine reference standards in various experimental models of indirect/direct nociception and neurotoxicity: writhing (acetic acid/magnesium sulfate), tail pinching, hot-plate, and capsaicin application

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methionine, one of the key ingredients, may aggravate metabolic acidosis and a compromised liver may be unable to properly metabolize the compounds