Kempuraj D, Thangavel R, Natteru P, Selvakumar G, Saeed D, Zahoor H, et al
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Administration of PINK1 B9 flies with Mucuna puriens extracts resulted in increased GSH amount and SOD activity, together with restoration of mitochondrial morphology in crop muscles, olfactory response, climbing behavior, extended lifespan, and delay in L-DOPA induced long term motor complication 31,32,33
This is a single-enzyme conversion, which makes NMN metabolically efficient compared to the two-step tryptophan pathway or the three-step NR-to-NMN-to-NAD+ route