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Pimozide (Orap), a medication used for Tourettes syndrome, shouldnt be combined with Lexapro as it can lead to increased plasma concentrations of pimozide and cause an increased risk of developing QT prolongation or ventricular arrhythmias

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In the STEP 1 study, 15% of semaglutide patients reported headaches compared to 12% on placebo

This means preserving muscle during weight loss with semaglutide may be important to reduce insulin resistance and prevent frailty in people with obesity. Haines said that more studies are needed to find the best way to lose fat but keep muscle when using GLP-1 medications.

Common gastrointestinal side effects persist across all treatment phases