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The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

Caspase-3 and PARP cleavage decreased (Pyo et al., 2007)

doi: 10.1016/j.bbamcr.2016.09.012 53 QinJGuoSYangJQaziIHPanBLvTet al

doi: 10.1016/S0076-6879(05)01001-3

It has been studied for its potential effects on sleep, chronic inflammation, longevity, aging-related conditions, DNA repair, and inhibition of tumor development [5, 6, 7, 8]

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