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Taken together with the findings of routine histopathologic examination and IHC, this genomic profile, with mutation in PRKAR1A only and monosomies of multiple chromosomes, including 1, 2, and 17, was diagnostic for MMNSTs
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Advances in neuroimaging techniques, particularly the measurement of glutathione (GSH) levels in the brain, which are important for antioxidant defense, by magnetic resonance, have gradually made this idea a possibility
