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The model is also consistent with published results that show that female mice are less susceptible than males to hepatotoxicity due to acetaminophen overdose and suggests that this might also be true for humans, though the human epidemiological data are contradictory

Furthermore, many lipidomic studies have demonstrated that PD-specific lipids are significantly altered in the brains and plasma of patients with PD, such as alterations in the lipid composition of lipid rafts in the frontal cortex