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Most of the HNSCC patients showed a c-MET mutation profile of Y1235D which was detected in higher incidence [83]

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Moreover, the IC50 values of MitoQ, DPI and vincristine are within the range observed for IMR-5/75 and Be(2)-C MNA cell lines ( Figures 2A, B

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In vitro assays show that retatrutide demonstrates enhanced potency at the human GIPR compared to natural GIP