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VEGF also regulates and shapes immunosuppressive TME by inhibiting dendritic cell maturation, preventing antigen presentation, and by polarizing macrophages toward an M2 phenotype

Concurrently, gut dysbiosis induces a leaky gut condition, allowing bacterial antigens to enter the portal system, contributing to maintaining a proinflammatory state within the hepatic tissue

6Camelo, C

The avian egg: chemistry and biology

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R.Mohseni-MoghaddamP.HosseiniM.GholamiL.BaluchnejadmojaradT.RoghaniM