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They are typically used for people at higher risk of heart attack, stroke or blood clots

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In a paper Bluestone and colleagues published in the AACR journal Cancer Immunology Research , they note that irAEs are either a consequence of an autoinflammatory response, caused by the activation of innate immunity, or an autoimmune response, indicated by the presence of autoantibodies and antigen-specific memory T-cell responses

Teicher, M.H., Pizzagalli, D.A

Tirzepatide offers similar benefits with additional metabolic advantages for some patients