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At ~5382 Da, FOXO4-DRI is above the typical renal filtration threshold (~60 kDa for globular proteins, but much lower for linear peptides), suggesting renal clearance may contribute to elimination

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Mechanistically: catalase mRNA +1.7-fold, SOD1 mRNA +1.4-fold, GPx1 mRNA +1.6-fold (RT-qPCR

Spatial and inferential statistics have been used to identify potential socio-economic and agency-related factors that influence climate action implementation