The anti-inflammatory and anti-oxidant mechanisms of the Keap 1/Nrf 2/ARE signaling pathway in chronic diseases
Morning: Gentle cleanser Vitamin C serum (allow full absorption) Hyaluronic acid serum Niacinamide (optional, can be in moisturizer) Moisturizer Sunscreen SPF 30+ Evening: Oil cleanser (if wearing sunscreen/makeup) Gentle water-based cleanser Copper peptide serum Additional peptide serum (optional, like Matrixyl ) Heavier moisturizer or night cream This routine separates vitamin C (morning) from copper peptides (evening) while delivering multiple anti-aging mechanisms
Abscisic acid (ABA) regulates many osmotic stress responses, including production of many osmolytes
References Abdulghani AA, Sherr A, Shirin S et al (1998) Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
A frequently cited 1992 study found that a single 3-gram dose of oral glutathione did not increase circulating levels in humans, and this finding was used to dismiss the entire category
The Immunological Genome Project: networks of gene expression in immune cells