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In people, fermentable fiber that raises SCFA production has been linked to higher GLP-1, though researchers are still working out how much of the effect runs through SCFA receptors versus other pathways

As predicted by preclinical studies with EPO (5) and ARA 290 (10,38), subjects receiving ARA 290 exhibited significant improvement in glucose control as shown by changes in Hb A 1c concentration

Available from: Accessed 11 Nov 2025 Damholt B, et al

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These improvements span the cardiovascular risk factors that metabolic syndrome creates