Compounded semaglutide is an option if there is a medication shortage or you need a customized dosage or formulation that is not commercially available
A 2024 double-blind randomized trial of 156 participants with early Parkinsons disease found that participants receiving a GLP-1 drug, lixisenatide, showed no progression of motor symptoms, compared to a measurable worsening on standard motor scales in the placebo group
Theoretical interactions exist with NSAIDs, anticoagulants, and CNS-active drugs
The relationship between adipose tissue (AT) and glucose metabolism in PWS remains largely unknown, although several studies have observed indices of lower IR compared to controls (166, 183, 184)
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Therefore, investigating the potential genetic benefits of GLP-1RAs for individuals with SA is of significant interest