In this process, due to the presence of tert-butyl protecting group on the side chain, an extra deprotection step is required
Inadequate conditioning or stretching an abnormal length-tension relationship and compliance of the thigh and calf muscles can increase strain on the patellar tendon and increase the risk of injury
GLP-1 receptor agonists and GIP/GLP-1 dual agonists carry a deep trial record: STEP studied semaglutide for weight management (NEJM 2021), SURMOUNT studied tirzepatide for weight management (NEJM 2022), and SURMOUNT-OSA studied tirzepatide for obstructive sleep apnea (NEJM 2024)
The most common side effects associated with semaglutide are nausea, diarrhea, and constipation
Keeping a simple journal of your symptoms and overall well-being can help your provider fine-tune your treatment plan
This is especially helpful when combined with a sustained workout plan and calorie management