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Gradual dose growth can help to mitigate these effects

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[21] The underlying principle, supported by guidelines from the Endocrine Society, American Association of Clinical Endocrinology, and American Gastroenterological Association, is that obesity is a chronic metabolic disease requiring ongoing medical management

They are not a replacement for emergency care, crisis support, or treatment for severe psychiatric conditions, but they can be considered as an adjunct when someone is medically stable and looking for more complete brain and mood support