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Larger, well-controlled human trials would strengthen conclusions (PMC

Discussion Oxidative stress reflects an imbalance between the production of reactive oxygen species and antioxidant defence [13]

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, & Yagasaki, K

Conclusion Although topical glutathione shows promise for dermatological applications, further larger randomized controlled trials with long-term follow-up are necessary to evaluate its utility more comprehensively in improving hyperpigmentation, erythema, and reducing free-radical damage