Consequences include enhanced mitochondrial membrane rigidity, disruption of plasma membrane integrity, and ultimately cell death
Glutathione exists in two states in the body: reduced (GSH) and oxidized (GSSG)
Researchers prepare fresh aliquots for each experimental run, document concentration calculations carefully, and confirm peptide identity by mass spectrometry prior to use in formal study protocols
Simultaneously, there is an enhancement of the expression of heat shock proteins (e.g., HSP70 and HSP90) and antioxidant proteins (e.g., heme oxygenase (HO-1), NAD(P)H dehydrogenase (NQO-1), glutathione reductase, glutathione peroxidase 2, and glutathione S-transferase pi (GST-pi)) [18]
doi: 10.2460/javma.2003.222.1713
Furthermore, a different study showed that the NF-B signaling pathway may be involved in the anti-inflammatory action of silver nanoparticles