Antioxidants also protect blood vessels from oxidative stress
Methods We devised an assay that measures the consumption rate of NADPH by glutathione-disulfide reductase (GSR) in the mitochondria and the cytosol of RAW264.7 macrophage cell lines
NIHs PubChem notes its investigational status, with no prescribing information available [pubchem.ncbi.nlm.nih.gov]
Amount to administer and recommended dosage
A recent meta-analysis of mixed evidence (5 RCTs 52,183,184,185,186 and 1 cohort study 187 ) in 2,071 people with T2DM or Parkinsons disease suggested antidepressant efficacy of the GLP-1RAs exenatide and liraglutide over 2452 weeks 188
Also derived from alpha-MSH same origin as KPV, completely different job Discovered accidentally in the 1980s at University of Arizona during tanning research men started getting spontaneous erections FDA approved in 2019 for hypoactive sexual desire disorder in post-menopausal women Works on the BRAIN not blood vessels like Viagra or Cialis Boosts dopamine = increases desire, motivation, and arousal from the inside out Works equally well for men AND women How it feels (real-world experience) Kicks in 45 minutes after injection Flushing/redness right after injection is normal Arousal builds gradually touch or kissing accelerates the effect significantly Hypersensitivity during the act Too much = nausea, elevated blood pressure, feeling "off" find your dose JD's experience at 2mg: incredible night, felt like a 16-year-old all the next day too much What to watch with PT-141 Can raise blood pressure at higher doses monitor if sensitive Nausea is common, especially early on usually a quick wave that passes Do NOT take with uncontrolled hypertension Don't combine with other vasodilators carelessly This isn't theory this is real-world experience working with hundreds of people and seeing what actually works
